Edema

 

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In normal and pitting edema, the fluid filtering out of the blood into the intercellular fluid contains solutes as well as fluid.

Usually, the amount of solute in the intercellular fluid keeps that fluid in balance with the cells, so that even when the tissue is edematous, the cells don't swell or shrink much.

If the blood is hypo-osmolar, though (as in somene who has drunk too much water), the filtrate out into the intercellular fluid will also be hypo-osmolar.

no change

shrink

swell

 
What will the cells do?